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Our Technology

Avectas is a cell engineering technology company, enabling drug developers to manufacture potent engineered cell therapies at therapeutic volumes, with high efficiency and with minimal cell disruption. Avectas technology delivers advanced molecules such as mRNA, proteins and gene editing tools to a range of cell types including T cells for immuno-oncology applications. Unlike the current industry standard of vector-free delivery methods, cells engineered with Avectas technology require no recovery time, leading to a shorter, simpler, more cost effective process. 

Our vision is to become the gold standard in vector-free intracellular delivery.


How It Works

Intracellular delivery is achieved by reversible permeabilization using a fluid handling process.

Step 1

A population of suspension or adherent cells can be modified within 4 minutes.

A population of suspension or adherent cells can be modified within 4 minutes.

Step 2

The cargo is mixed with the proprietary delivery solution and applied to the cells with precise control of volume and application time.

The cargo is mixed with the proprietary delivery solution and applied to the cells with precise control of volume and application time.

Step 3

The delivery solution gently permeabilizes the cell membrane and the cargo rapidly diffuse into the cell.

The delivery solution gently permeabilizes the cell membrane and the cargo rapidly diffuse into the cell.

Step 4

The permeabilization solution is replaced with a recovery solution which results in high cell viability and functionality levels.

The permeabilization solution is replaced with a recovery solution which results in high cell viability and functionality levels.