The Solupore® Research Tool (RT) offers reproducible cell engineering for non‑viral RNA delivery. Its gentle mechanism maintains cell viability while delivering efficient payloads and is ideally suited for discovery and translational workflows.
Designed for simplicity, the RT combines activation, transfection and early expansion steps into a single, closed consumable. A compact footprint makes it ideal for small labs, while automated controls minimise hands‑on time.
Efficient HDR and knock‑in editing of induced pluripotent stem cells while preserving pluripotency.
Introduce mRNA or RNP complexes into primary cells for transient expression studies.
Reprogram hematopoietic stem/progenitor cells and peripheral blood mononuclear cells without affecting viability.
Independent studies have demonstrated that Solupore® preserves cell phenotype and viability while delivering high transfection efficiencies. In Kavanagh et al. (Cytotherapy 2021), non‑viral delivery using Solupore® showed minimal perturbation compared with conventional methods.
Across diverse cell types—including T cells, NK cells and iPSCs—the RT consistently achieves high editing efficiencies with minimal cell activation. Customers have used the system to perform CRISPR‑mediated knock‑ins, prime editing and mRNA transfection with excellent viability and functionality.
Contact us to explore how the Solupore® RT can accelerate your discovery and translational programs.