SoluScale™ platform

Scalable and Flexible.
From manual process
development to automated
manufacturing

The proprietary single-use, closed SoluScale Cell Chamber (SCC) can be used manually, then moved directly into our compact, automated manufacturing unit (AMU), a GMP-ready instrument for scaling.

SoluScale Platform Translatability

Translatable Process SCC to AMU
  • SCC process yields ~2e9 LiveCells per run
  • Easy to use incubator based process
  • Readily translates to the AMUprocess with similar fold growth
  • Comparable CAR expression,maintained at >55% for both SCC and AMU process
Comparable Fold Growth per Donor
>55%CAR Expression

Start manually

The SoluScale Cell Chamber is designed to be used as a standalone in a biosafety cabinet. You can develop your process without an initial capital investment in automation.

Want to get started?

Talk to us

Performance

• High Transduction efficiency: > 60%

• Potent cytotoxicity with controlled VCN number

• Cells retain favourable phenotype with low T cell exhaustion

Automate with confidence

De-risk the move to automation

The SoluScale Cell Chamber (SSC) moves directly onto the AMU eliminating the need to re-optimize your process.  
One unified workflow with maximum flexibility
Closed System with activation, transduction, expansion and harvest decreasing handling and contamination risk.
Digital monitoring with a GMP-aligned regulatory package
Proprietary platform integrates into existing workflows with minimal disruption to your existing processes.
Plan your scale out

Designed for manufacturing

Energy efficient:

Low thermal output that does not materially warm the GMP suite.

Smallest footprint:

Compact design is 20-55% smaller than competitor instruments, reducing the GMP facility space required.

Flexible throughput:

From one instrument to multiple instruments as your production needs to grow.

Digitally monitored and controlled:

Supports consistent, reproducible manufacturing and GMP compliance.

SoluScale™

Enhance patient access. De-risk your development journey.

You can scale to clinical and commercial manufacture by running multiple SoluScale instruments in parallel, while maintaining the same consumable and process.

This seamless and cost-effective approach uses the same well-defined process from day one, accelerating the path to clinic while significantly reducing the cost.

SoluScale™Talk to our experts

>200

Full scale development runs completed

9x

Throughput of a manual, open process

3,000

Batches per year from a 1,000ft2 manufacturing suite

Get in touch

We would love to hear about your project and explore how we could help meet
the challenges ahead.

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R&D Facility

Ground Floor Building 10, Cherrywood
Business Park, Co. Dublin D18 T3Y1

North American Office

245 First Street, Suite 1800,
Cambridge, MA 02142, United States

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